High Throughput Screening for Novel Anti-Inflammatories (Progress in Inflammation Research)

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Author : Michael Kahn
Genre : Science

Summary : Combinatorial chemistry in conjunction with High Throughput Screening (HTS) is revolutionizing the drug discovery process. Yet, we have much to learn about the integration of these powerful techniques with information from genomics, proteomics, computation and pharmacokinetics before dramatic increa

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Author : Trevor T. Hansel
Genre : Medical

Summary : Chronic obstructive pulmonary disease (COPD) ranges amongst the commonest diseases in the world. The relentless progression of the disease causes a pressing need for a better understanding of and therapies for COPD. This volume provides state-of-the-art information on the pathophysiology of COPD inc

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Author : Gordon L. Letts
Genre : Medical

Summary : Chemokines play an important role in recruiting inflammatory cells into tissues in response to infection and inflammation. They also play an important role in coordinating the movement of T-cells, B-cells and dentritic cells, necessary to generate an immune response (response to injury, allergens, a

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Author : G. A. Higgs
Genre : Anti-inflammatory agents

Summary : Cytokines have become established as key mediators of the signs and symptoms of inflammatory diseases such as arthritis, dermatitis, asthma and multiple sclerosis. Furthermore, they are involved in the cascade of events leading to cardiovascular shock and are major regulators of the function of immu

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Author : Jay Mehta
Genre : Medical

Summary : In the last ten years, major strides have been made in defining the presence and role of inflammation in atherosclerosis as well as in injury to the tissues that occurs after episodes of ischemia and reperfusion. In sixteen chapters, written by world-renowned individuals from different countries, th

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Author : Daniela Salvemini
Genre : Inflammation

Summary : Literally thousands of papers have been published on nitric oxide over the past ten years. But there is no single monograph available that has previously attempted to summarize the important features of the roles of nitric oxide in inflammation. The voluminous literature regarding the incredible ran

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Author : Giora Z. Feuerstein
Genre : Medical

Summary : Heart failure research is a most active area of research in academic, industrial and government-sponsored research and receives intense clinical attention. The recent recognition that inflammation is a risk factor and prognostic factor for heart disease has laid ground for preventive medicine and ev